Our laboratory studies the pharmacology of neuromodulators in the context of development of novel therapeutic interventions for neuropsychiatric illnesses. Presently, our primary focus is on subtypes of G-protein coupled receptors, such as dopamine, muscarinic, and cannabinoid receptors and their coupling to distinct effector and transduction pathways.
We seek a highly motivated Postdoctoral Fellow or Research Staff with expertise in brain slice electrophysiology and interest in molecular pharmacology. In addition to work in brain slices, the successful candidate will receive training in cultured cell systems using novel approaches such as bioluminescence resonance energy transfer (BRET) and biosensor-based functional measurements to achieve more comprehensive understanding of receptor biology.
Our laboratory is currently involved with collaborations in the areas of medicinal chemistry, computational biophysics, and rodent behavior studies at the NIH Intramural Research Programs, complementing our efforts in molecular pharmacology and brain slice electrophysiology.
Location/Region: Boston, MA (02115)